RNase H

Expression and identification of HBV RNase H gene

乙型肝炎病毒核糖核酸酶H基因表达及鉴定

Roles of RNase H in inhibition of SRS mouse leukemia virus ( srsv ) expression by antisense oligonucleotides

RNaseH在反义寡聚脱氧核苷酸抑制小鼠白血病病毒表达过程中的作用

The results indicated that AAS of survivin could be effectively selected in vitro by random oligonucleotide library / RNase H cleavage combining with computer software analysis , whose corresponding AS-ODNs could block the biological functions of survivin gene .

说明运用随机寡核苷酸文库RnaseH酶切割与计算机分析相结合的方法，在体外有效筛选出survivin的反义核酸结合位点，其相应的反义寡核苷酸能阻断survivin基因的生物学功能。

RNase H enzymes are ribonucleotide-specific endonucleases that cleave the RNA portion of RNA-DNA / DNA or RNA / DNA duplex , which activities depend on a divalent positive ion , releasing oligoribonucleotides with 3 ′ - OH and 5 ′ - Phosphate ends .

RnaseH是一类特异性内切RNA/DNA杂合体中RNA链的酶，其活性依赖于二价金属离子，酶切产物具有5′-磷酸末端和3′-羟基末端。